I will discuss knot-like defects in CS theory with complex gauge group SL(N), in the context of its connection with 3d N=2 theory (the so-called 3d-3d correspondence). I am hoping to discuss this problem from a number of different perspectives, including cluster algebras, state-integral models, 3d N=2 non-Abelian gauge theories, 5d N=2 SYM, and holographic dual, and discuss the consistency checks as well as new predictions/implications. This talk is mostly based on my recent papers with D. Gang, N. Kim and M. Romo.