Conformal symmetry relates the metric on AdS_2 x S^1 to that of S^3. This implies that under a suitable choice of boundary conditions for fields on AdS_2 the partition function of conformal field theories on these spaces must agree which makes AdS_2 \times S^1 a good testing ground to study supersymmetric localization on non-compact spaces. We evaluate the partition function of N=2 supersymmetric Chern-Simons theory on AdS_2 x S^1 using localization, where the radius of S^1 is q times that of AdS_2. With boundary conditions on AdS_2 x S^1 which ensure that all the physical fields are normalizable and lie in the space of square integrable wave functions in AdS_2, we find that the result for the partition function precisely agrees with that of the theory on the q-fold covering of S^3.