The study of possible constraints on RG flows is an important question in our understanding of quantum field theory. In this talk I will discuss a constraint which arises by considering the spectrum of BPS excitations (an H-theorem). Examples are found in the context of four-dimensional supersymmetric quantum field theories with enough supersymmetry that the BPS spectrum is explicitly computable. Among others, we will discuss applications in the context of Maruyoshi-Song flows. [for zoom link please contact jung-wook(dot)kim(at)qmul(dot)ac(dot)uk]