These lectures will review recent developments surrounding the infrared sector of gravity in (3+1)-dimensional asymptotically flat spacetimes (AFS). In the first part of the course we will introduce soft theorems which govern the low-energy scattering of massless particles such as photons and gravitons. We will explain how these are related to classical observables known as memory effects and discuss their application to computing infrared-finite collider observables and gravitational waveforms. In the second part, we will introduce the notion of asymptotic or large-gauge symmetries and use it to derive the infinite-dimensional asymptotic symmetry algebra of (3+1)-dimensional AFS, also known as the BMS algebra. We will show that the conservation laws associated with these symmetries are equivalent to the Weinberg soft graviton theorem. Time-permitting, we will discuss some implications of these ideas for non-AdS holography.